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Chlorpromazine Hydrochloride Tablets
Tablets Prescription Medication
Category:
Other series
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Product Description
· National Medical Insurance Products
· National Essential Medicines List
Specifications: 25mg | 50mg
Drug category: Western medicine
National Medical Insurance: Class A
Indications:
1. Effective in alleviating positive symptoms such as excitement, agitation, hallucinations, delusions, thought disorders, and behavioral disturbances. Used for schizophrenia, mania, or other psychotic disorders.
2. Relieves vomiting caused by various factors, as well as persistent hiccups.
Pharmacology and Toxicology:
This product is a phenothiazine-class antipsychotic drug whose mechanism of action primarily involves blocking dopamine receptors (DA2) in the mesolimbic and mesocortical pathways. It also exhibits broad-spectrum antagonistic effects on dopamine (DA1) receptors, serotonin receptors, M-type muscarinic acetylcholine receptors, and α-adrenergic receptors. Additionally, at low doses, this drug inhibits dopamine receptors in the chemoreceptor trigger zone of the medulla oblongata; at higher doses, it directly suppresses the vomiting center, thereby producing a potent antiemetic effect. Furthermore, it suppresses the thermoregulatory center, leading to a decrease in body temperature, which can fluctuate in response to environmental changes. By blocking peripheral α-adrenergic receptors, the drug induces vasodilation, resulting in reduced blood pressure, and it also exerts moderate effects on the endocrine system.
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